Inhibition of Post-Heparin Lipolytic Activity by Lipid Peroxide
نویسندگان
چکیده
منابع مشابه
Lipolytic Activity of Post-heparin Plasma in Hyperglyceridemia.
A standard assay has been developed for the lipolytic activity of post-heparin plasma permitting rate measurements with zero order kinetics over wide ranges of enzymatic activity and concentrations of plasma glycerides. Measurements were made in 60 subjects with hyperglyceridemia, 18 of whom had been further subclassified by dietary studies into either fatinduced or carbohydrate-induced types. ...
متن کاملLipolytic Activity of Post-heparin Plasma in Hyperlipemia and Hypolipemia.
• The demonstration of a heparin-stimulated lipemia-clearing (lipolytic) factor in the plasma of animals and m a n w suggests that a deficiency of this factor may lead to the production of hyperglyceridemia in atheroscle-rotic patients. A number of investigators have compared the lipolytic activity of plasma from atherosclerotic patients and from normal individuals after giving them small doses...
متن کاملPlasma post-heparin lipolytic activity in rats with nephrotic syndrome.
A marked elevation of plasma lipoproteins is found in rats with nephrotic syndrome induced by puromycin aminonucleoside (Marsh and Sparks 1979a; Gherardi, Vecchia and Calandra 1980; Gherardi and Calandra 1982). Although the hepatic production of lipoproteins is increased in nephrotic rats (Shafrir and Brenner 1979; Calandra, Gherardi, Fainaru, Guaitani and Bartofek 1981) the mechanism of plasma...
متن کاملPost-heparin lipolytic activity and tissue lipoprotein lipase activity in the alloxan-diabetic rat.
It is widely assumed that measurement of lipolytic activity in post-heparin plasma (PHLA) reflects the activity of the enzyme lipoprotein lipase in extrahepatic tissues, i.e. adipose tissue, muscle and the heart. Apart from the findings of low PHLA in patients with Fredrickson’s type I (fat-induced) hyperlipoproteinaemia (Fredrickson, Ono & Davis, 1963), in which a defect in tissue lipoprotein ...
متن کاملEffect of estrogen on post-heparin lipolytic activity. Selective decline in hepatic triglyceride lipase.
The rise in plasma triglyceride (TG) levels associated with estrogen administration has been thought to arise from impaired clearance because of the uniform suppression of post-heparin lipolytic activity (PHLA). Recently PHLA has been shown to consist of two activities: hepatic TG lipase and extrahepatic lipoprotein lipase (LPL). To determine whether estrogen might induce a selective decline in...
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ژورنال
عنوان ژورنال: The Journal of Japan Atherosclerosis Society
سال: 1982
ISSN: 0386-2682,2185-8284
DOI: 10.5551/jat1973.10.4_767